His brother, the writer and critic William Michael Rossetti, described her as having "greenish-blue unsparkling eyes, large perfect eyelids, brilliant complexion and a lavish heavy wealth of coppery golden hair."
The number of paintings and drawings Rossetti did of her are said to number in the thousands. Perhaps best known among Rossetti's works of Siddall is Beata Beatrix, which depicts a praying Beatrice (from Dante Alighieri) and was painted in 1863, a year after Siddall's death.
In 1852 Siddall began to study with Rossetti. She produced many sketches, drawings, and watercolours as well as one oil painting. Her sketches are laid out in a fashion similar to Pre-Raphaelite compositions illustrating Arthurian legend and other idealised medieval themes, and she exhibited with the Pre-Raphaelites at the summer exhibition at Russell Place in 1857.
Siddall overdosed on laudanum in February 1862. A stomach pump was used, but to no avail and she died on 11 February 1862.
Beata Beatrix, by D. G. Rossetti
Portrait by D. G. Rossetti
Regina Cordium, by D. G. Rossetti
Lady Affixing Pennant to a Knight's Spear,
by E. Siddall
Lady Clare, by E. Siddall
Madonna and Child, by E. Siddall
Ophelia, by J. Everett Millais